Thiamine deficiency disorder

Thiamin deficiency disorder
"Beri-beri"

 

Aetiology:

A disease 2ry to thiamine(vitamin B1) deficiency affecting the nervous system(dry beri-beri) or the cardiovascular system(wet beri-beri).

Clinical Picture:

1)Dry beri-beri: peripheral sensory neuropathy:

• Subjectively there is pain and paraesthesia in the limbs,espcially distally
• Objectively there is:

*Superficial sensory impairment of the stock and glove nature.

*Deep sensory loss specially distally with absence of deep reflexes.

2)Wet beri-beri: congestive heart failure.

3)Cerebral type(werni cke's encephalopathy): amnesia,ophthalmoplegia,nystagmus&ataxia.

Treatment:

1)thiamine 100 mg daily snd vitamin B complex.
2)Diet rich in vitamins and low in salt.
3)Digitalisation and diuretics in in case of heart failure.